| Controller Type | Serial ATA |
| Country of Origin | Taiwan |
| Depth | 9.6" |
| eSATA, Network (RJ-45), RAID Supported | Yes |
| Ethernet Technology | Gigabit Ethernet |
| Expansion Slot Type | PCI Express 3.0 x8 |
| Form Factor | Desktop |
| Height | 6.5" |
| Maximum Power Supply Wattage | 250 W |
| Memory Technology | DDR4 SDRAM |
| Number of 2.5" / 3.5" Bays, Number of Hard Drives Supported, Number of Solid State Drive Supported, Number of Total Expansion Bays | 6 |
| Number of Hard Drives Installed, Number of Solid State Drive Installed | 0 |
| Number of Network (RJ-45) Ports | 4 |
| Number of Total Expansion Slots, Packaged Quantity | 1 |
| Number of USB 3.0 Ports, Total Number of USB Ports | 3 |
| Operating System | DiskStation Manager |
| Processor Core | Quad-core (4 Core) |
| Processor Manufacturer | AMD |
| Processor Model | V1500B |
| Processor Speed | 2.20 GHz |
| Processor Type | Ryzen |
| Product Family | DiskStation + |
| Product Line | DiskStation |
| Product Model | DS1621+ |
| Product Name | Synology 6 Bay NAS Diskstation DS1621+ |
| Product Series | + |
| Product Type | SAN/NAS Storage System |
| RAID Levels | 0, 1, 5, 6, 10, Basic, Hybrid RAID, JBOD |
| Standard Memory | 4 GB |
| Width | 11.1" |