Simport Histosette II - Lids Only For Tissue Cassettes In E-Z Load M482-12LI Lab Equipment | spectraservices.com

Synonyms: Anti-DCP1 Decapping enzyme 1, homolog A; Anti-SMAD4IP1; Anti-SMIF; Anti-Smad 4-interacting transcription factor; Anti-Smad 4-interacting transcriptional co-activator Storage: -20C UNSPSC Code: 12352203 Features and Benefits: Antibody BioguaranteeEvaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more. General description: Dcp1 colocalizes with Dcp2 in distinct cytoplasmic foci along with other proteins involved in the 5' to 3' mRNA decay. These foci are termed PB (processing bodies) or DCP-bodies. Application: Anti-DCP1A antibody produced in rabbit is suitable for immunoprecipitation at a working concentration of 5-10 ++g using cell lystes of HEK-293T, indirect immunofluorescence at 2-5 ++g/mL using paraformaldehyde-fixed NIH-3T3 cells over-expressing human DCP1A or using paraformaldehyde-fixed HEPG2 cells and western blot analysis at 1-2 ++g/mL working concentration using cell lysates of HEK-293T. It was used as a primary antibody at a working dilution of 1:200 in the immunofluorescence experiment of HeLa cells treated with 5-fluorouracil to study the assembly of stress granules based on RNA incorporation. Application: Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.Immunofluorescence-cell culture cells (1 paper) Biochem/physiol Actions: Dcp1 cleaves the m7G mRNA cap in the 5' to 3' mRNA decay pathway, in association with Dcp2 and Hedls complex. Decapping is a critical and highly regulated step in the turnover of mRNA which involves decapping enzymes that hydrolyze the cap structure at the 5' mRNA. Immunogen: synthetic peptide corresponding to amino a

SIMPORT E-Z LOAD LIDS ONLY AQUA QTY(2000) - SIM