Ideal for packaging of biological and diagnostic reagents that require aseptic dispensing or addition of supplements by syringe. Bottles are leak-proof, sterile, and offered in a variety of sizes. The silicone/PTFE closure with septum provides a PTFE fluid contact surface that is inert and nonstick to ensure fluid integrity. Bottles and closures are sterile to 10-6 sterility assurance level. Biologically tested bottle and septum closure meet USP Class VI and European Pharmacopeia Abnormal Toxicity standards. No cytotoxic. Bottles are packaged in shrink-wrapped trays in double poly-bagged cartons for cleanroom applications.